Closed-Loop Stimulation

Define neural events to trigger customized stimulation algorithms in real time using the included Xippmex MATLAB interface.

  • Ripple Grapevine systems are able to implement low-latency closed-loop recording and stimulation algorithms.
  • Use the MATLAB interface to define neural signals and trigger customized electrical stimulation in real time.
Example of a closed-loop stimulation experiment
closedloop

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Open-Loop Stimulation

Electrically stimulate with custom stimulation patterns, while simultaneously recording with fast-settle circuitry.

  • Ripple Grapevine systems include an intuitive graphical interface to set up biphasic pulses and pulse trains for open-loop stimulation regimes.
  • Our Front Ends have fast-settle circuitry for low-latency recovery after stimulation.
Example of an open-loop stimulation experiment
openloopstim

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Neuromodulation

Use Ripple Grapevine systems for any neuromodulation implementation.

  • Examples include selective, long-term spinal cord or peripheral nerve stimulation, and event-triggered closed-loop stimulation.
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Brain-Machine Interface

Simultaneously drive your robotics, exoskeletons, or computer interfaces while recording up to 512 channels of biopotential signals (e.g. spikes, LFPs, EEG, ECoG, and EMG).

  • Ripple Grapevine systems feature Analog and Digital Front Ends to provide signals to record from and control external devices.
Example of a brain machine interfacing stimulation experiment
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Online Decoding

Synchronize your cortical, neuromuscular, analog, and digital data sources for online decoding.

  • Ripple Grapevine systems are designed for high-channel count electrophysiological recording, and provide a MATLAB interface capable of implementing user-customized online decoding.
  • The Xippmex online MATLAB interface can be used to alter recording parameters or process the incoming data for real-time online decoding.

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Neuroprosthetics

Use Ripple Grapevine systems for neuroprosthetic research and implementation.

  • We specialize in high-channel count electrophysiological recording and stimulation, ideal for either online decoding for brain-machine interface neuroprosthetics, or closed-loop neuroprosthetics that control external devices and provide sensory feedback via electrical stimulation.
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Epilepsy Monitoring

Connect to all passive electrodes on the market, including microelectrode arrays, ECoG arrays, and EEG caps.

  • Ripple Grapevine systems are ideal for both chronic and acute epilepsy monitoring with high-channel count electrophysiological recording.
  • We can connect to any passive electrodes on the market, including microelectrode arrays, ECoG arrays, and EEG caps commonly used for epilepsy focus localization.
  • The Grapevine system meets relevant safety standards for implanted human research.
Example of a epilepsy monitoring experiment
ecogepilepsy

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Intraoperative Mapping

Use our systems for intraoperative exploratory mapping with high-channel count electrophysiological recording.

  • We can connect to any passive electrodes on the market, including microelectrode arrays, deep brain stimulating electrodes, and ECoG arrays commonly used for intraoperative mapping.

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